![]() Niacin-induced anicteric microvesicular steatotic acute liver failure. However, keep in mind that an EFSA report from 2012 suggests that up to 6,000 daily is safe, demonstrating its strong. Their efficiency of converting food into energy may also increase metabolism. ![]() Niacin, in particular, can help break down carbohydrates, fats, lipid forms, and sugars, which lead to a healthy digestive cycle. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. The most common dosage range for taurine is 5003,000 mg per day (2, 5). Digestive tract functioning can improve with sufficient vitamin consumption. We link primary sources - including studies, scientific references, and statistics - within each article and also list them in the resources section at the bottom of our articles. Applies to niacin: compounding powder, oral capsule, oral capsule extended release, oral. Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. Commonly reported side effects of niacin include: pruritus, nausea, and flushing. Other side effects include nausea, vomiting, pruritus, hives, abnormally high liver enzymes, and constipation. However, the exact mechanisms remain unclear.Įxperts theorize that high doses of niacin overwhelm the nicotinic acid receptors, which are a type of protein responsible for flushing out excess amounts of niacin from the body. The most common side effect of niacin supplementation is flushing. They believe the mechanism for damage occurs in the liver due to chemical reactions and changes that take place. How so?Īccording to a 2018 study, both quick-release and extended-release niacin have links to liver damage or toxicity. The damage often becomes apparent after a dose increase. Certain high doses have associations with liver damage. However, high doses and long-term treatment can lead to issues with the liver, such as hepatitis and liver failure. The Office of Dietary Supplements (ODS) notes there have not been any reported adverse effects as a result of consuming niacin that occurs naturally in foods. Prescription-strength nicotinic acid can play a role in reducing low-density lipoprotein (LDL) cholesterol, or “bad” cholesterol, while increasing levels of high-density lipoprotein (HDL) cholesterol, or “good” cholesterol. Niacin - also called vitamin B3 - is a water-soluble vitamin naturally present in many foods.It is also available as two dietary supplements: nicotinic acid and nicotinamide.Ī healthcare professional may prescribe nicotinic acid to help treat high cholesterol. Share on Pinterest Stefania Pelfini, La Waziya Photography/Getty Images
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